The AGI is working across a number of different fields to deliver to projects where genomic data is vital for delivery of practical impacts to stakeholders
Data generation technology has advanced significantly in recent years, making it faster and less expensive to sequence genomes and generate diversity datasets. This has led to increased research in fields such as medicine, agriculture, and conservation biology. Whole genome sequencing can be used for a variety of purposes, such as identifying genetic diseases, determining ancestry, and studying evolutionary relationships between different species. With projects related to agriculture, environment, conservation and the circular economy, AGI simplifies the data generation and analysis process which allows stakeholders to focus on the impact side of the work rather than data generation, preliminary analysis and management.
Australian Pest Genome Partnership (APGP)
The APGP proposal aims to generate high quality chromosomal genome assemblies and population resequencing data for Australia’s highest priority pests.
The Australian Pest Genome Partnership (APGP) is a partnership between CSIRO, Australian Research Data Commons (ARDC), Australian National University (ANU) and Biocommons Australia. This project delivers easily accessible reference quality data assets for few critical Australian pests and invasive species with environmental, agricultural and public health impacts relevant to Australia. APGP aims to develop green workflows, data standards and analytical practices around pest-related genomics. This will facilitate the development and uptake of modern genome-based approaches to the management of these species.
The data assets aggregated or generated in this project will be split across three categories:
- Environmental pests: invasive mammals such as rodents, cats and rabbits or locally invasive coral predators like Crown-of-Thorns starfish
- Health pests: mosquitoes such as Aedes aegypti, and various Anopheles and Culex species that can vector diseases such as malaria, dengue, zika and Japanese encephalitis viruses.
- Agricultural pests: invasives and pests such as noctuid moths, mites, aphids, flies and beetles
High quality chromosomal genome assemblies for Australia’s highest priority invasive and native pests. Incorporating and enhancing existing datasets (for example, Lepidopteran and Dipteran data comprising over 1000 whole genome data sets) and adding data as needed for high priority species e.g. invasive ants and feral cats. The project will deliver wet-lab workflows and software pipelines to the wider community along with interactive access to analytical tools (like browsers etc) and computational pipelines.
Currently Australian relevant pest species genomes and data are hosted in a wide variety of often incomplete online resources, custom data storage or only publicly available as raw data. We use the community focused CSIRO Data Access Portal to deliver a long-term, version-controlled and continuously curated repository for all raw and processed data, linked to interactive pipelines and adding value through integration for related pest groups.
Stakeholders and end users of this project include Australian agricultural, environmental and public health managers, research organisations and federal and state governments. The ultimate beneficiaries will be the Australian people who will benefit from reduced public health risks and the reduction of impacts these species.
• Tom Walsh, CSIRO
• Rahul Rane, CSIRO
• Phil Taylor, Macquarie University
• Ary Hoffman, The University of Melbourne
• Owain Edwards, CSIRO
• Dan Andrews, ANU
• Amanda Padovan, CSIRO
• Wee Tek Tay, CSIRO
• Andy Bachler, CSIRO/ANU
• John Oakeshott, Macquarie University
• Karl Gordon, CSIRO
• Susan Maas, Cotton Research and Development Corporation
• Jeevan Khurana, Grains Research and Development Corporation
• Greg Chandler, Horticulture Innovation Australia
• David Wachenfeld, Great Barrier Reef Marine Park Authority
• Jamie Hopkinson, Queensland Department of Agriculture
• Kelly Hill, South Australia Research and Development Institute
• Tanja Strive, Centre for Invasive Species Solutions
• Scott Buchanan, Wet Tropics Management Authority